Health issues

Abstract: Glyphosate, the active ingredient in Roundup®, is the most popular herbicide used worldwide. The industry asserts it is minimally toxic to humans, but here we argue otherwise. Residues are found in the main foods of the Western diet, comprised primarily of sugar, corn, soy and wheat. Glyphosate's inhibition of cytochrome P450 (CYP) enzymes is an overlooked component of its toxicity to mammals. CYP enzymes play crucial roles in biology, one of which is to detoxify xenobiotics. Thus, glyphosate enhances the damaging effects of other food borne chemical residues and environmental toxins. Negative impact on the body is insidious and manifests slowly over time as inflammation damages cellular systems throughout the body. Here, we show how interference with CYP enzymes acts synergistically with disruption of the biosynthesis of aromatic amino acids by gut bacteria, as well as impairment in serum sulfate transport. Consequences are most of the diseases and conditions associated with a Western diet, which include gastrointestinal disorders, obesity, diabetes, heart disease, depression, autism, infertility, cancer and Alzheimer’s disease. We explain the documented effects of glyphosate and its ability to induce disease, and we show that glyphosate is the “textbook example” of exogenous semiotic entropy: the disruption of homeostasis by environmental toxins.

Werewolf wrote:

TR1 wrote:There is ZERO proof that GMOs have an effect on health.

In fact if you actually did your research, you would know that study was criticized and withdrawn (the mouse one).

I got bad news for you btw, chances are you have eaten plenty of food that can be classified as GMO.

Studies that counter such studies like the Pharma industry, when their bullshit moneymakers have been proven to cause to many sideeffects with almost no benefits that were intented, the same happens here the food industry is a monopoly in the US with such garbage.

If you did your research you would know that this GMO crap is nothing else but a money maker and a biological weapon, they indeed to harm health to such an extent that drinking of bleach seams healthy.

sepheronx wrote:http://tass.ru/en/non-political/794664

This is bad.  Russians shouldnt be this stupid, they have good education.  So there needs to be a major push to fighting HIV and getting these people away from breeding or something.  Cause HIV is a serious issue.

We forecast this number to reach one million by the end of the year," he said. "If our forecasts come true, the number of HIV cases may double in one or two years."

kvs wrote:

sepheronx wrote:http://tass.ru/en/non-political/794664

This is bad.  Russians shouldnt be this stupid, they have good education.  So there needs to be a major push to fighting HIV and getting these people away from breeding or something.  Cause HIV is a serious issue.

Sorry but this is complete hysterical BULLSHIT.

We forecast this number to reach one million by the end of the year," he said. "If our forecasts come true, the number of HIV cases may double in one or two years."

LOLWUT

A 100% per year growth rate?  WTF is this clown smoking?   AIDS didn't appear in Russia last year.  It has been going strong since
the 1990s and earlier.   There has not been any new strain that evolved in Russia so this surge in cases is simply not credible.  If
there was some sort of surge in poverty but then we would have seen this phenomenon in 2009.  

Vadim Pokorvsky looks to be looking for more money.   He should be fired on the spot.

kvs wrote:I should add that HIV is a problem and I am not smug about it.   But 100% annual growth rate claims are
detached from reality.

As you note, there has been a lot of progress in treating HIV even if there is no cure.  It has been
"tamed" so that the infected can survive basically indefinitely.  Twenty years ago it was a still a death
sentence (with a roughly 10 year delay).  

The Guardian writes:

   Vadim Pokrovsky, head of the federal Aids centre in Moscow, predicted this month that at least two million Russians are likely to be officially registered as HIV-positive within five years, and a total of three million will have the virus.

All pretty worrying, except when we stop to consider that he also said the following – in 2002:

   We’re talking about one-to-two million infected now, and in 2005, we could be talking about five-million being infected, and these are realistic, even conservative figures.

In reality, as of 2015, around 0.6% of the Russian population is officially registered as HIV positive. This is probably fairly comprehensive, since around 20-25 million people (one sixth of the population) are tested for it every year; though it should be noted that the unofficial figure is estimated to be around 50-100% higher.

Even so, while that’s pretty bad by industrialized country standards, of course – about 3-10x higher per capita than in West European countries, twice higher than in the US, and about the same as in Ukraine and Estonia – but is nowhere close to the cataclysmic levels you see in Sub-Saharan Africa.

The alarmist articles that you see and have been seeing in the press since about 2000 about millions and even tens of millions of Russians succumbing to AIDS in the next X years are fantastic in the literal sense of the word.

The reality is that in Russia, as in the rest of the ex-Soviet world, AIDS is primarily driven by injecting drug users (IDUs). This is unlike in Sub-Saharan Africa (SSA), where transmission is primarily sexual, whose particular virulence there is probably due to its specific environment (cultural acceptance of soft polygamy, widespread malnourishment/compromised immune systems, and states too fiscally weak to support mass antiretroviral therapy).

Hence the complete failure of models that relied on applying SSA HIV dynamics to Russia at predicting the course of the epidemic there. The graph below is from a 2006 report (pp.56) that collated all of the most high profile projections. The most pessimistic projection, that by Ruhl et al., featured Pokrovsky as a coauthor, incidentally, while the other highly pessimistic estimate came from Nicholas Eberstadt, an AEI demographer who has always been extremely bearish on Russia’s demographic prospects.



I copied down the most important graphs from that report in this old post. In short, more realistic modeling that treats IDUs as the main driver and doesn’t foresee any major deviations from current sexual and drug usage preferences from today’s norms sees a rapid rise in infection rates throughout the 2010s, peaking around 2020, but never reaching much more than 1% of the population even at its peak, followed by a steady decline reaching an asymptote at around 0.5% of the population (note that this assumes no decline of Russia’s huge problems with injecting drug usage which is likely very pessimistic).

This process has “momentum,” on account of the relatively huge numbers of IDUs in Russia, and is very difficult to stop. But the chances it will spread to the general population to any degree – i.e., to people who don’t have first-order sexual relations with IDUs – is all but zero. And this is indeed what we are seeing happen.

The actual trends are closely tracking another model, the TFRI, as well as of an original model to the cited report (pp.78):



This is not to say that Russia’s “conservative” approach to fighting AIDS is without fault, nor that people like Pokrovsky have no right to make a din over it in the media (as he has in fact been doing for the past two decades). It is virtually certain that avoiding the government funding needle exchanges causes more harm than good, though its worth noting that syringes can be freely bought at any well-stocked pharmacy (though, of course, heroin addicts are not known for their high future time orientations). Methadone treatment is a much more questionable case, there being a legitimate debate over its efficacy; it is more addictive even than heroin. Treatment isn’t a problem, even if prevention is. There is near universal access to anti-retrorival therapy amongst registered HIV positive people.

The Orthodox Church’s “malign” influence on this issue is typically exaggerated; for instance, it does not oppose condom use. It is not at all clear to me to what extent progressive attacks on the “conservative” approach are merited. One of the root problems is that so many people feel so despondent or reckless that they are getting addicted to hard drugs. Religion and/or sports – the current emphasis – can indeed in many cases offer an alternative. Society has indeed become less favorably disposed to homosexuality in the past decade, in large part due to state policy. One can say this promotes “ignorance.” But it’s also a fact that HIV spreads much more easily via anal sex, and if it becomes less accepted as a result of changes in social mores, well, that statistically means fewer infections. Both at the national level (in Russia, as well as in Ukraine) and at the international level (they might take the anti-progressiveness a notch to far but the prevalence of AIDS is near zero in the Arab world) it is pretty clear that all else equal – i.e. adjusting for human capital, etc. – it is the more conservative/religious regions that have fewer problems with AIDS in the first place.

And I’m sure it’s possible to come up with plenty of counter-arguments to the above. But that’s not the main point, which is that at the end of the day, what we are ultimately dealing with here is not some kind of runaway pandemic that will result in SSA-level infections rates “in a few years” but a very much epidemic that will burn fiercely in affected communities (primarily IDUs and their close sexual partners) but remains contained in the IDU-sphere and peaks around 2020 and then declines.

Likewise the real debate is not about how long it is before Russia collapses from AIDS (and brain drain, and Eurabia, and the Yellow Peril, and…) but whether the epidemic peaks at, say, 1% of the population, or 1.5% of the population, and whether it happens in 2018 or 2022. It’s a lot less fun than constructing apocalyptic scenarios, sure, but it’s also more realistic.

sepheronx wrote:

kvs wrote:I should add that HIV is a problem and I am not smug about it.   But 100% annual growth rate claims are
detached from reality.

As you note, there has been a lot of progress in treating HIV even if there is no cure.  It has been
"tamed" so that the infected can survive basically indefinitely.  Twenty years ago it was a still a death
sentence (with a roughly 10 year delay).  

I recall reading about a vaccine a year or two ago, where nurses and doctors could receive the vac, so that they could not contract it from a patient.  Dunno how true or effective it is, but if it is true, it should become mandatory all over the world for young people.

Regular wrote:

sepheronx wrote:

kvs wrote:I should add that HIV is a problem and I am not smug about it.   But 100% annual growth rate claims are
detached from reality.

As you note, there has been a lot of progress in treating HIV even if there is no cure.  It has been
"tamed" so that the infected can survive basically indefinitely.  Twenty years ago it was a still a death
sentence (with a roughly 10 year delay).  

I recall reading about a vaccine a year or two ago, where nurses and doctors could receive the vac, so that they could not contract it from a patient.  Dunno how true or effective it is, but if it is true, it should become mandatory all over the world for young people.

You can probably survive for long time in UK where medicine is well developed(*in some cases it's archaic and it some it's one of leading in the world) and free, but in Russia and in rest of Eastern Europe HIV is a death sentence. Even today. Antiretrovirals therapies are crap, immune systems eventually can't cope and it leads to AIDS or early death even before it  
What about HIV vaccine? Any more info about it? AFAIK there were so many tries, but all failed. There is such thing as PEP in UK for example. And it's free. http://www.nhs.uk/chq/Pages/1840.aspx?CategoryID=73 Not a vaccine but..

Even having sex with HIV infected WOMAN You have small chance of infection. 0.1 % if sex was unprotected and vaginal. It's faggot and druggie disease really.  

Siphilis on other hand is.. bitch of a disease Can be caught by kissing too. Hard to detect when it's too late and etc. Infects the spine and fucks up Your life before You know it. And my Russia and Eastern Europe is leading there.

Viktor wrote:WoW .... great  

Russia sees drug addict numbers fall by one million - anti-drug agency

Karl Haushofer wrote:

Viktor wrote:WoW .... great  

Russia sees drug addict numbers fall by one million - anti-drug agency

Wonder if this is a result of decreased heroin flow from Afghanistan or improved methods of preventing drug use?

Good news anyway.